I have 2 sewing tables on wheels, so I have tried a couple setups. My last version was back to back, so that there was a large area in the middle to support a quilt from either machine. Functionally, it was great, but I missed being able to glance up at the TV from one of the machines. So I am now trying end to end, floating down the center of the room. TV sight is perfect from both machines, and it gives me more open wall space for storage options, but I miss the other arrangement with quilt support. I underestimated how important this is.
My cutting table is also on wheels. I leave it against the wall until I need to walk around it for basting a quilt.