I think most printing isn't on the straight of grain and I never expect it anymore. I expect more out of woven stripes, plaids, etc.
Some of it is just because of the manufacturing process but often it is designed in to have a slight drift to the design.
It's always a decision for me to use it on grain or on pattern -- most times I take the extra couple of minutes to fussy cut on the pattern, but sometimes it doesn't matter.
We had a thread on panels recently, oof! I got a terrible panel that I would have been made about had I bought it for full price instead of at the thrift store. Sometimes printing and such is just bad. It's not the store's fault and it is sort of up to us as consumers to make sure there are no flaws in what we buy.
My story isn't as good maybe as a typo, but I was recently given a fabric with "snowflakes" on it. Except they were designed with 8 sides and snowflakes have 6 sides. Still they were clearly snowflakes even if not in this reality...