I have had times where something in my quilt bothered me but it was too late to change. Well, after awhile I forgot all about it and have even looked for it if I remembered. So there is something to be said for being too picky I think.
I can't abide cut off points but a turned seam here and there I can live with. I do the best I can without going crazy.
Perfection would kill quilting for me.