I'm another one who has worked in a kitchen with the off-sided sink. My friend loved it and it worked well for her, I have other friends who they haven't worked so well for. I was on the less impressed side of the fence. For me practically wise, I'm right handed and my dishwasher is to the my right, I'd prefer the larger sink to be closer to the dishwasher.
When we do redo our kitchen, or we may just need to replace the original sink (it's actually wearing out), I will be going for the single large size or what I call "lasagna disk soaking size". I think I will miss having the divided sink because I've gotten used to having a clean side and a dirty side but there is more often when I want to soak an entire pan instead of dipping in half at a time.
We were actually looking at dishwashers today. It's a shame I can't afford to replace my cabinets (old style built ins that are not standard size) but I can make my life significantly better with a new dishwasher and sink
