this will be a rather large quilt based on those block sizes. I've made lots of t-shirt quilts that have different size blocks and have found that the best way to figure your lay-out is to simply lay the blocks out on a bed. That way you can play with the background colors and size at the same time. Not sure why, but it always makes more sense to me to do these type of t-shirt quilts as strip quilts instead of rows. Your goal is to not have any Y seams. Once I've kinda of figured out a layout, I then get my EQ8(used to use graph paper which works fine too) and sketch it in so that I have a better idea of the filler strip sizes I need. Good luck and post a picture.