It would handle in a similar way to the denim jeans quilts. Reminder - quilts of old were made of whatever fabric was available - it all works, it just handles differently. Because it is thicker, I would use either no batting or a very thin batting. Often times I will only use wide flannel for projects like this because I want a little something to buffer the seams but not add too much bulk or weight. And, while I am not one who usually prewashes, whenever I use flannel for anything, I prewash everything.