My favorite scissors, hands down, are Kai. I have several pairs, 4 of which I just sent off to Kai for sharpening. They are micro-serrated, which means the fabric won't slip between the blades. They also have a rubber coating on the handles, which makes them softer on the hands.
A couple years back, there was someone here on the board who was a lefty and was looking for something specific, some specialty applique scissors, I think? She was frustrated because she couldn't find what she wanted anywhere. Based on several encouraging responses here, she contacted Kai and they custom-made her a pair, exactly what she wanted, and if I remember right, didn't charge anything over and above what the regular price would have been. She was very happy.
