I've used raw edge applique for every one of my labels. They seem to be doing fine. I started out using Wonder Under on the entire label, fusing it down, and then zigzagging the edges, but I also attach to the backing prior to quilting so that the quilting goes through the label so there's no ballooning. If I were going to attach it after the quilt was quilted, I would definitely use the fusible web on the entire piece plus sew the edges down. I like to attach prior to quilting because I'm not sure I'd like being able to see the outline of the label on the front of the quilt? I also don't hand sew at all, so everything is machine for me. YMMV