Test it first. Take a white cotton kitchen towel, get a corner of it damp, and rub it on the suspected fabric. If the towel changes color, you have a bleeder.
If it does bleed, I have had the best results with the Vicki Welsh method of treating it. It works better than Retayne, Synthropol, color catchers, and multiple washings.
https://www.colorwaysbyvicki.com/upl...edingquilt.pdf