Instead of thinking "Get rid of stuff.", maybe try thinking that there is someone out there that would love it more than you do.
Most quilt guilds have outreach programmes to finish tops for charity or neighbourhood programmes where non-quilters can learn to quilt. These always need donations of fabric, patterns, etc.
Make it a Good Samaritan project to help out these places and reward yourself with a less cluttered room, while you're at it.
Watson