I try to have no real differences between my charity quilts and my other quilts, sometimes yes there are greater design considerations. But more than once someone has chosen one of my "available" tops over one that I actually made for them. I don't buy shoddy fabrics, I buy Hoffmans and Moda and Batiks and all sorts of things, and am perfectly happy with the quality of a 1980s Cranston/VIP floral should I happen onto 6 yards of it.
The market I make most of my quilts for is primarily foster kids. While not everything I make appeals to me and can be rather taste specific, I believe it appeals to someone especially someone young. But yes, you could be quite happy with one of my quilts and not another so I prefer groups that let the kids pick and not just hand them one. The quilts need to be durable and machine washable. With all donation quilting, you have to be prepared that it is gone out of your life and may or may not be appreciated -- and the same is true for the quilts we give our friends/family.
The link I posted isn't the most thrilling back in the world, but I considered one from that line or similar to be suitable for my own Bonnie Hunter project from last year. Think that one was $14.95/yard??