The only negative I have heard so far about using digitally-printed, 100% cotton is that the dye does not penetrate the cotton deep into the fabric and so your sewing may inadvertently reorient undyed material closer to your top as your machine sews along, leaving a faint trail of white in spots of your stitching. It may be related to the age of the needle or thickness of the thread but the lack of saturation of the dye through the fabric (depending on the manufacturer??) is nothing you can do anything about.
I have no experience with digital fabrics that I am aware of, btw. I have seen no trails of white peeking through the dye that wasn't my thread :-). Try buying a digital panel from your LQS and sew on it to see what happens before you invest a bunch of money in digital fabric. Tell us your results, too. Good luck!