Thanks everyone. My heart wants to believe she will come home, but my head really doesn't believe it. I put flyers on everyone's doors on my street and put up flyers on lamp posts on the streets on either side of mine. One of my neighbors also lost a cat the same way this year. And one of my other neighbors said they had seen coyotes at the end of our street. But I have lived in this house for 20 years and have never seen coyotes this close. We do live in the desert, so coyotes do roam close in, so it is possible.
Thank you again for your thoughtful responses.