It may depend on what kind of ink it is. Ball point ink is removable. Gel ink is not, no matter what. I found this out the hard way - hubby dropped a gel ink pen on a nice dress shirt and it wicked up an ink spot about 2 inches in diameter. I replicated the stain on scraps, then tried every remedy I could find posted on the internet. Nothing worked. I finally gave up when I came across a law enforcement website that recommended using gel ink pens to write checks, because bad guys couldn't bleach the ink out.