I do not personally have a Tutto but I have admired them a lot. The only drawback I can see is the small wheels - I live in the country and some of the local quilt shops are also rural based... the little wheels (regardless of brand) do not do well on gravel lots/driveways... because of that, I use a rolling duffle bag - it has handles for lifting, it's meant to roll across any surface. They do lack padding, not sure if that is important to you.
FOR EVERYONE - for safety of you and your machine, please use the seatbelt to lock it in place. It can be a lethal projectile in case of accident. If you put yours in the trunk, it's good to secure somehow to protect the machine itself. If you use a hatchback style, be sure to anchor/secure somehow so it doesn't come crashing forward.... it sounds alarmist, but I have a friend who almost had a fatal injury from something that seemed harmless that became airborne in an accident.