I love my Accuquilt GO Big Electric cutter. It was either that or stop quilting because my back would no longer allow rotary cutting, so the cost did not deter me. I don't use a rotary cutter to cut pieces from yardage, I use a scissor, because those pieces don't need to be exact.
I think this would be impractical if you don't have a dedicated table to set it up on, because it is so heavy. The dies don't always cut perfectly, so I often have to cut a thread after the shape has been cut. You also have to pick out threads that get stuck in junctures on the dies. But from my perspective, this is just routine stuff you get used to.
The fabric waste was a real shocker at first, but I was never that upset about wasting fabric so it no longer fazes me. I just want to quilt, so I accept whatever is necessary with the fabric cutter.