I’ve made several orphan block quilts and love putting them together. If you like puzzles, this is a similar process. I begin with the larger blocks placing and spacing them out. Then begin filling in with smaller blocks and leftover tiny blocks. Occasionally I will have to add a strip or make something to fit the need. Using the larger blocks as a divider for large rows or sections helps. (Sorry but that part is difficult to explain. Hopefully, that makes sense).