If I don't wash my room-Pergo floors, curtains, everything in the room AND alllll my bedding-My nose and throat let me know. I used to take weekly allergy shots, but now I use Allegra every day, and have recently noticed some improvement using a Netty pot (non-invasive).
Also, I have to wash all my bedding with De-mite or in hot water. Needless to say, my quilts take a beating. So, I tried a duvet.
However, a duvet 1, hides the quilt and 2, is a chore to use when removing the quilt before washing (every two weekes. I went back to using a quilt.
I finally made a simple panel quilt that I wash frequently.
(I tied it and machine quilted it-it's strong.)
All the above help me.
Good luck!