I am not the queen either, but have done some of it. There are a few things you have to think about in advanced:
Which stitches are you using to applique. You can use a zig zag, invisible hem stitch, blanket or double blanket stitch, but you can also use a decorative stitch.
If you want your stitches to be hidden, use the smallest stitch possible and use thin thread, the same color of the applique.
You may want your stitches to show, in this case you can use a thread that contrast your fabrics rather than matching, use a larger stitch, and a thicker thread.
Wonder under or any other fusible will make your applique stiff. If you are making a wallhanging, it may not matter, so you can use it under the entire surface. If you want your quilt to be flexible, it may be a good idea to just use it on the edge of the applique. I have also used liquid stitch. Apply to the edge of the applique. when is dry, heat set in place with the iron and then decorate the edge, or use any stitch you want to use to applique.