if you're quilting on a frame or hoop with stand, try John James Twin Pointed Stab Stitch needles. the eye is in the middle of the shaft and there's a very sharp point on each end. it takes practice and you need good light in the work area. if you master the technique, though, it's much easier on the wrists and hands. you don't even need a thimble. it's also much easier to work around curves; change directions; etc. you'll need to buy extras when first learning because the needles are fragile. you'll probably break a few while you learn. instructions are on the back of the pack.
Hancock's of Paducah seems to offer the best price for them:
http://www.hancocks-paducah.com/Item--i-JJ-620-DE