As far as fabric, I would be fine for a very long time. Well, not fine, but I could sew. It would be so hard to not buy more fabric. I don't have a stock pile of batting, so I would have to get creative there.
Just even thinking about this question makes me feel like I need to rush to the fabric store again, or at the very least, start ordering like crazy on the internet.
I have told my kids that when I die, they have my permission to sell all the stuff in my sewing/craft/sanctuary room, and all go on a cruise. I am sure there would be enough for tickets and even souvenirs. Yes, it is that much stuff.