My full time job interfers with my sewing on a regular basis. I work with a computer all day, so I am usually suffering from eye strain when I get home from work. If not, I try to spend some time sewing. I usually schedule Saturday mornings for sewing. If I am working on a deadline project, I will sew a couple of hours each night that I am free. Occasionaly, I will take a Monday or Friday off as a mental health day from work and spend lots of time sewing. I usually can get my sewing room straightened up on these days too. One of my favorite things to do is to let my family and friends know that I will be going out of town on Friday evening and returning late Sunday evening. And then I go up to my sewing room and sew most of the weekend without the phone ringing off the hook. I tell DH that I will be on a quilting retreat, he asks where, I say upstairs and that is all that needs to be said. Neither of us get too excited about cleaning as long as it is picked up we are both very good at ignoring the dust.
I am able to keep the house about 20 minutes away from clean by following the FlyLady system. I found the Flylady in a post to a thread a couple of years ago. She has a wonderful system to help get it all done and have a lot of free time each day too. www.flylady.net.
I am dream of retiring though, and until then I will continue to collect fabric, patterns, and notions. I will be so prepared when that wonderful day arrives.