Oh my that is some stain. If all else fails maybe you tea dye it?! That stain is really dark. Good luck. It’s a cute quilt.

Thanks, everyone. I think I will get some Retro Clean and give that a try. I'll let you know how it turns out.

It looks more like an espresso drink was spilled on it. Either way use hints for removing coffee stains first.

Coffee was my first thought also.

Dawn seems to work for some stains.

Let us know how you come out on this! That's one big stain but, if the quilt has already been washed and dried, I would expect it to be pretty much a permanent thing by now. Such a cute quilt that I hope you can save it. If the stain doesn't come out, perhaps it can best be rescued by simply removing that bottom row of doggies and put a border on it. At least, the stain doesn't appear to be up into the body of the quilt and mostly there at the bottom.

While it won't help this quilt, maybe it would help some "doothless" folks if a "care of" set of instructions were included with every quilt.

I once was told that Biz works well for stains on quilts. It is enzymatic and shouldn’t harm the fabric. I find that it works better than oxiclean for laundry stains.

I use BIZ..it used to come in powder only...Fill washer up with hot water put in BIZ, let t dissolve. Let water cool to cold. Put the quit in and soak it over nite. Using same water put in some Blue DAWN, maybe 1/4 cup..wash on gentle cycle...Take quilt out , if stains still on quilt repeat process . I have used this method for years with good results.
Do not dry quilt in dryer until all stains are gone. Heat sets the stains oin.

BIZ is my go-to for stains. For a while I was not able to get in the grocery store, but now it is back. I soak lots of stuff in BIZ overnight before washing.