Ive tied a fleece quilt and it went very well. I was warned about how difficult it might be to machine quilt it, and at that point I was not in any hurry for difficult.

I have just finished a lap quilt with the chenille backing, I only stitched in the ditch, I like how they feel with the fleece back, they are so cuddley feeling. Free motion, is not a good idea because of the stretch, as much as I like doing free motion. For me, I would not hand quilt or tie, but SID instead. Just my thoughts.