This spray Super 77 is not water solvable, so when it is dried it will not wash out so there will not be that bubble effect. That seems a plus factor for this brand of adhesive.

I think it would be easier to use MistyFuse:
http://www.amazon.com/Mistyfuse-Mist.../dp/B000PFPSJI

Is there some reason you don't want to use a fusible web?

I use 505 or sullivans all the time.

Spraying was the first method I learned for machine applique. Thought it was really neat until I had shifting on the fabric.

Now I use paperbacked fusible or if I want to turn it, I use a very thin fusible - can't remember the name - bought it at the quilt store and still have a lot of it in a ziploc bag. Less bulk with paperbacked fusible.

If you do several layers, then trim the paperbacked fusible to where it's only about 1/4" wide around the edge of the design before you iron it down on the fabric. You can keep triming the unneeded fabric as you go.

If you are a hand quilter I would suggest using the no-name applique technique. I can't find the link right now but if someone else knows it, please post it - thanks!

Ghostrider, The reason is only that I tried both methods on a test applique and the spray adhesive seemed to be both easier and more accurate. The fusible web I was using is Pellon Wonder-Under Transfer Web and it didn't hold the fabric as firmly as I was wanting it to. I think I am accustomed to using spray adhesive because I use it so much with the hooping for embroidery, although for that I use a temporary adhesive. For my appliques, as as for many of yours I'm sure, the built up thicknesses of the layers gives a desireable 3 dimensional effect.

Have you pre washed your fabrics? I have had trouble using wonder under if my fabrics aren't washed. It won't stick to the fabric because of the chemicals used in the manufacturing of the fabric.

Auntpiggylon, Yes I had prewashed those fabrics. I was still less than thrilled with wonder under. I did use it to laminate the top fabric of 4 placemats to the bottom fabric,
but pealing the paper off without part of the adhesive coming with it was so difficult that I switched to the Super 77 spray adhesive for the next 8 placemats. It's quick and easy but has a drying time.

I use Elmer's School Glue around the edges and iron it dry. The glue stick can fray the edges as you apply it.

You can iron parchment paper to the Misty Fuse for a very light weight paper backed fusible. Light enough to quilt through.