Welcome, suecq.

I have made a two sided quilt, but I just treated it as a single quilt and quilted it to suit the first side. The echoed flowers may look a little strange on the second side, but my daughter hasn't complained. If I had been concerned, I could have done an allover meander.
http://www.quiltingboard.com/picture...e-t192881.html

And another. This one has some thread painting, but again, my son hasn't complained. http://www.quiltingboard.com/picture...r-t174360.html

Do a reversiable quilt.

I always piece the front and backs. I like having two different sides and I can use smaller pieces of fabric for both and don't have to worry about buying too much "yardage." I use a thin cotton batting and have no problems quilting through the three layers, and even with all the seams it's usually not as thick as QAYG can be sometimes. I haven't gotten the hang of FMQ yet so I just quilt it using all-over lines, either diagonals or SITD on the front if it will look ok on the back too.

When I make double sided quilts I do an all over quilting design instead of a block by block design. I've never had a problem at all and they look fabulous. I mainly make double sided quilts because I like the versatility of them. The way I table baste also makes it so both sides are centered :)