Sounds like this friend wants the clothes made into a throw so that she can wrap it around herself and feel as if her "life partner" is giving her a hug. Please don't make something to hang on the wall - it won't provide the comfort she is looking for. As long as the clothes that you use is cotton or a blend, they should work fine. Using a simple design should work and larger blocks would probably allow her to retain the memories better. I don't know whether there are any tshirts but if there are, and one of them is a favorite, the throw could have the tshirt in the middle, surrounded by blocks of cotton/blend fabric.