There are a few books that have quilt blocks that are for each of the fifty states. That may be a way to start. Or you could create blocks that create the feeling of home... and what promotes that feeling/memories... trees... autumm.. green spaces.. family ... activites she participated in.
My family creates a quilt for each member when they graduate from high school We include in the blocks the interests and events of their life. One quilt we used fabric pieces/scraps from clothing that person wore , and called the quilt "the threads of your life".