I use Elmer's school glue to hold my quilts together. I've tried spray basting, but the layers still shift. I have had absolutely no problems with using school glue - nothing shifts, it is easy to hand quilt through, and it washes out beautifully. I iron the layers together as I glue baste them so everything is dry and ready to go as soon as I finish putting the layers together. I follow the same process as Jeanne S, but use very, very thin lines of glue drizzled on from about 24 inches above the quilt.