Look for local organization that are caring for or and welcoming refugees. There are several in my community. One is church affiliated but another is not. They are just there to help the families get accustomed to the US. Polish their English, obtain jobs, learn how to get from place to place, get their children in schools and tutoring adults and children. These folks often come with very limited materials goods to make their life warm and comfortable. A quilt is often a touch of American that will give them warmth and comfort.
Also consider colleges or universities that have students who have aged out of the foster care programs in your state. These students seldom have what is needed to supply their dorm rooms, specifically bedding. One of our local quilt guilds took on the project of making quilts for each former foster student registered at Western Michigan University. The quilts were well received and there were some extra quilts for newly admitted students later in the year. The quilt made 130 and the university needed 70-80.
Just a few more ideas to what has already been posted. Happy quilting!