Are you putting both front and back side of binding on with stitching once and catching both sides? I tried that once and had horrible results!
Instead, I machine sew the binding to the back of the quilt, then fold the binding over to the front and stitch it as down as close to the folded edge of the binding as I can. It doesn't come out too bad. While I won't win any prizes for my binding technique, the job does get done.
I tried hand sewing the binding once - it took forever, I stink at hand sewing, and my hands simply don't like to do fine work anymore.