I open a window (even in the winter) and would definitely cover a hardwood floor.
I prefer 505 basting spray because some of the others really gummed up my needle.
Remember that you just need a light spray and I have found it really helps to iron both sides and then let it sit over night before I start quilting.
I stick a few pins in just to help hold it while I'm pushing it around quilting.
Once you get a system to your work it goes well but it seemed like such a big thing the first couple of times I tried it (once outside on the snow covered deck- bad idea).
-good luck