What a predicament! Both offer advantages and both would leave me happy . . . and exhausted.
Paducah would offer beautiful and fantastic quilts, beyond my ability . . . and there would probably be crowds. Missouri Star would offer a more relaxed environment and lots of opportunity for window shopping and buying. My feet would hurt after a few hours in both places but MSQC offers lots of places to sit and ponder and dream. I am also fascinated how one company can bring new life to a town.
If you need some additional excitement, there are many attractions an hour or so away - St. Joseph (old Missouri River town) to the west, Kansas City to the south (with a variety of attractions), Jamesport (Amish and art communities) and Hannibal (the home of Mark Twain and river town) to the east. And if you haven't got enough fabrics and shopping in Hamilton, there's some wonderful small quilt shops within an hour's drive.
Wow! What a decision you have!