Yes, and I have. If a piece is something that I will never use, I get rid of it. Done, period, and out the door. What is the purpose of keeping it when I will never use it because of the quality of the fabric? I have had a few that went directly to the cutting mat for chopping up for dog beds.
Part of the process is knowing yourself, your style of quilting your color schemes and ... well just be honest with yourself. If ya won't use it then why keep it.