usually all you have to do is remove the batting from the package and shake it out...and let it breath for awhile...i drape mine over the couch or a chair...or toss it on the bed for a bit usually while i'm loading the quilt, the creases are gone by the time i am ready for the batting. the creases relax. if they were very stubborn (i've never had this problem) putting it into the dryer for a few minutes will more than likely work well. i'd be very careful trying to iron it...seems like that would be much more of a pain than worth the trouble, plus the chance of stretching it out of shape is very likely.