I've never used this method, but I think you could pop your knot into the batting when starting as always when hand quilting, then make the stitch as shown in this video, but instead of taking that last stitch all the way through to the back, just run it through the batting to the next spot you want to make a flystitch. Hope I'm right, and not misleading you, anyway here's a little youtube video on the fly stitch.
http://www.youtube.com/watch?v=PF90YGbrmMg