I almost always use cotton Warm and Natural or White and Natural or a cotton blend 80/20 Hobbs. Sometimes I feel a quilt needs polly. So most of the quilts in my home are cotton batting but the few that are polly are the most loved by my children. The last polly bat quilt I did was for a baby. He was very small at birth and the Warm and Natural cotton just seemed it would be heavy. I much prefer to machine quilt cotton bat quilts over polly bat though. For hand quilting I like the polly. For our family the Warm and Natural cotton wears much better then the polly batting but it probably has to do with the brand polly batting I use.