My very first quilt was out of flannel, the Around the World pattern with about 3" squares. First, wash and dry the flannel at least three time. Many folks recommend starching. I didn't know enough to do that. I found that it stretched and to make the ends come out even I stitched halfway down a block and then turned it around an stitched back the other way. Very tedious and doesn't allow for chain piecing. But, remember, it was my first quilt and I didn't know any better. I used 1/4" seams, and stitched in the ditch and the quilt is 7 years old, well worn and washed and dried many times and all the seams and quilting have held up great. I used warm and natural as the batting and flannel backing. Good luck with it and post a picture when it is done!