Most of these suggestions are good. I would have her checked by a vet for a UTI. Clean the litter box every day. Cats can't handle dirty litter boxes. I have a female that likes to pee on bathroom rugs and dirty clothes. All bathrooms have the rugs hanging on the shower door and no clothes on the floor. (makes for a semi tidy house). Also make sure the litter box has easy access. Might even want to put two boxes on seperate floors or rooms. I have 8 indoor cats and so far so good.