Margaret's Hope Chest is a very worthwhile quilting charity that has several programs where they provide quilts to those in need, especially children. They also have a "birthday" quilt programs where you can make a quilt for a child's birthday. The kids in the program all have at least one parent in prison.
I have sent them many quilts and I will send a few more this week. They take quilts of all shapes, sizes, colors and skill levels.
To read more about them visit their website:
http://www.margaretshopechest.com/index.html
They also have a blog:
http://margaretshopechest.blogspot.com/
and
http://wrappedinhope.blogspot.com/