Each technique of quilting has its challenges - hand, domestic machine and long arm. Each one requires practice and it is just a matter of finding your preference. I quite frankly,like all of them. I can't afford a long - arm; I do some hand quilting, and it takes a long time, so I mostly run my quilts under the domestic sewing machine because it is quick and has some nice customised quilting designs that one can only do this way, as do the other methods .
I'm not much help to steer you in any direction - why not have a go at all of them and you will soon find which you like?