My SIL and I do much the same things so we rarely exchange handmade items (my SIL made my son a quillow when he was 5, when he wore it out he asked her for another one and she's been happily replacing them at his request ever since).
Since we don't live near my DH's family, and his family is huge and they all pretty much live in the same area, I really don't know what their likes or dislikes are, and I would love to give them things so what I do is mail a box of things I've done to one of the nephew's wives, who in turn offers them to any family member that would like them. I send a box a couple of times a year. There are never "leftovers" and I know that family members are taking what they really like.