I was in my late 40's when a cancer scare caused a hysterectomy to come about. Menopause comes on all at once that way. I tried premarin for about a week and didn't see any difference. I was working at the local colleges stable cleaning stalls at that time. Here it is the middle of winter and I hurry out of the stall to strip down to a tee shirt. Had the other girls laughing after they found out it was just too darn hot in there ( middle of winter about 25 degrees) I lived through it that was about 15 years ago. still ocasionaly get hot flashes and the covers and dogs go flying off the bed in the middle of the night. Oh well I hope this too shall pass. Hang in there you aren't crazy. At least that was what I chanted to myself.