It all depends on what you'd like to learn. Some people start out hand quilting, some tie, some machine a simple stitch (like stitch in the ditch or straight lines), some make a top and have someone else quilt it and a few people do the quilt as you go.
I have a domestic machine but rarely use it to quilt....I only piece on it. Do whatever works for you. I'd start with a table runner or something small like a crib quilt just to be sure you have the hang of it before tackling a larger project---but that's just me.
There are a lot of resources between the forum, youtube & blogs for online advice. If you choose the quilt as you go method, be sure to check out your local library for some reference books. Georgia Bonesteel books are of that method and have been out long enough that libraries generally have them.
Best Wishes!