My DH had them and passed out at work..he ended up in the hospital for a week before he passed several of them. The DR told him it's the closest thing to labor pains that a man can have. I was pregnant with our 1st DD at the time...Good luck to your Sis..Cranberry juice is good for the kindeys too..but the water is the most important. Does she take vitamin suppliments? Calcium is a contributing factor to them I have heard too..