Funny you should ask - I just went to the dermatologist yesterday because I have a horrible rash on my two index fingers. And it started before Christmas - I was making a fleece LSU blanket for Great Nephew and binding it with LSU cotton print that had not been washed. I kept putting neosporin on it but it just got worse. So now I have a prescription for a cream of some kind (haven't picked it up yet) that he said should clear it up in a couple of weeks. I hope so - it is ugly and painful! I almost never use fabrics without washing it, and that one I had used for a hurry-up Christmas present pillow case. Won't make that mistake again!