I am new to it but am reading an excellent book on machine quilting - how to use a walking foot for SITD and way beyond (which I can't remember the author of and am at work) and she shows examples of doing just that. The photos show how the hand stitching in areas she wants to highlight contrasts nicely with the precise machine look of SITD or near-ditch lines. Also she suggests trying wavy embroidery stitches.