I only take the quilt off and turn it if it is a different thread color. I did a quilt that was white thread for the entire body and red thread for the borders. So I did the red top border then did the body in white BUT YOU MUST BASTE DOWN YOUR SIDES THAT IF YOU ARE NOT QUILTING THEM. Then I did the bottom red border and flipped the quilt. As long as you baste the sides as you are quilting, then I find no problems with them stretching or shrinking.
Rose