I have been told (at our local Joanns) as long as the bar code is different it can be used. Two coupons can't be used on the same item. Different coupons used on different items. Have never had six coupons but have had four or five and they scaned OK. The cash register makes the decision. If there is a different item that can be used for each coupon the register will take it. I have never had to go through the line twice. BrendaK