It is not a good idea but I do all the time - but I am very careful and go slowly when I do this. If you hit a pin just right, you can really mess up your machine. After working for Viking, I have seen some very unhappy machines that ran over too many pins.
If I have a block or a border that I need to "ease" into place and it would require many pins, I do what we used to do in clothing construction with sleeves. I run a tad longer stitch just inside the seam allowance and loosen the tension. I then pull one thread to tighten up the stitches (like you would gather but without the gathers - does this make sense??). Works great for easing one block to another when they are a bit off.